CHAPTER 4
Connective Tissue
61
A:
Nuclei of
f broblasts
are
elongated and, when inactive,
these cells have little cytoplasm.
The F broblasts are formed and
reside in the connective tissue;
they are also called
f xed cells
.
B:
Plasma cells
are char-
acterized by cartwheel (clock-
face) nuclei showing the alter-
nating distribution of the het-
erochromatin (
dark
) and the
euchromatin (
light
). The pale
(
unstained
) area of cytoplasm
in each plasma cell is the loca-
tion of the Golgi complex,
which is also called the
Golgi
zone
.
(
GZ, Golgi zone.)
C:
A
mast cell
has a sin-
gle, oval-shaped nucleus and
granules in its cytoplasm. In
parafF n H&E–stained sections,
these granules are typically
unstained, but they appear red
in sections of plastic- embedded
tissues stained with a faux
H&E set of dyes.
D:
An
eosinophil
has a seg-
mented nucleus (two lobes,
usually) and numerous eosino-
philic (
red
) granules F lling the
cytoplasm. Eosinophils, mast,
and plasma cells are
wander-
ing cells
(±ig. 4-1A).
E:
Black particles F ll the
cytoplasm of these active
macrophages
; the nuclei are
obscured by the phagocytosed
materials.
F:
Each
adipocyte
contains
a large droplet of lipid, appear-
ing white (
clear
) here because
the fat was removed during tis-
sue preparation. The nucleus
of each cell is pushed against
the periphery of the cell.
±igure 4-2A–D.
Cells in the connective tissue o± the small intestine.
ModiF
ed H&E,
3
1,429
±igure 4-2E.
Macrophages in lung tissue.
H&E,
3
2,025
±igure 4-2±.
Adipocytes in connective tissue o± the mammary gland.
H&E,
3
373
Connective Tissue Cells
A
Fibroblasts
Fibroblasts
Fibroblasts
B
GZ
GZ
Plasma cell
Plasma cell
GZ
Plasma cell
C
Mast cell
Mast cell
Mast cell
D
Eosinophil
Eosinophil
Eosinophil
E
Macrophages
Macrophages
Macrophages
F
Adipocytes
Adipocytes
Nuclei of the
Nuclei of the
adipocytes
adipocytes
Adipocytes
Nuclei of the
adipocytes
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