CHAPTER 3
Epithelium and Glands
43
CLINICAL CORRELATION
Figure 3-15C.
Salivary Gland Swelling.
Salivary gland swelling
with infl ammation (
sialadenitis
) is
a clinical condition that can result from blockage of a duct
or ducts, so that saliva is not able to exit into the mouth.
This causes the saliva to back up inside the duct, resulting
in gland swelling. The patient will feel pain when chew-
ing food. The most common cause of blockage is a
salivary
stone
(
calculus
), which forms from salts contained in the
saliva. A blocked duct and gland F lled with stagnant saliva
may become infected with bacteria. A typical symptom of
a blocked salivary duct is swelling that worsens just before
mealtime. Sometimes, a small stone may be ejected into
the mouth without medical intervention. A dentist may be
able to push the stone out by pressing on the side of the
obstructed duct. Removal of a stone may require surgery
or lithotripsy treatment by focused, high-intensity acoustic
pulses.
D. Cui &L Lynch
Inflammatory cells
Distorted cuboidal cell
Stone in lumen (calcium)
C
Stratif
ed Cuboidal Epithelium
Stratified
Stratified
cuboidal
cuboidal
epithelium
epithelium
Stratified
cuboidal
epithelium
A
Figure 3-15A.
Stratif
ed cuboidal epithelium,
salivary gland.
H&E,
3
175; inset
3
234
Stratif
ed cuboidal epithelium
lines the ducts of
the salivary glands. This uncommon type of epi-
thelium has a very limited distribution. It may be
found forming the ducts of some large exocrine
glands and sweat glands. It functions to form a
conduit for the secretory products of the gland.
This type of epithelium is composed usually of
only two layers of cuboidal cells, with the basal
layer of cells often appearing incomplete.
D. Cui
Cuboidal cell
Cuboidal cell
Connective tissue
Basement membrane
B
Figure 3-15B.
A representation o± stratif
ed cub-
oidal epithelium in the duct o± a salivary gland.
Stratif
ed cuboidal epithelium
usually has only two,
occasionally three, layers of cuboidal cells. The top
layer is composed of
uni±orm cuboidal cells
, whereas
the basal cells sometimes appear to form an incom-
plete layer (±ig. 3-15A). Cells in stratiF
ed cuboidal
epithelium often have smooth apical surfaces, and
nuclei are centrally located.
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